Indianapolis Colts S Antoine Bethea and WR Anthony Gonzalez are among 11 players who the team has listed as being out for the preseason opener.

Bethea, one of four active-roster starters who will miss Friday’s game, sustained a broken bone in his hand late this week and Colts Head Coach Jim Caldwell said he likely will play with the hand wrapped when he returns.

Caldwell said Gonzalez will miss with a mild hamstring injury.

Also, the Colts have activated WR San Giguere (leg) from the Physically Unable to Perform list.

The other players listed as out are:

* TE Dallas Clark (concussion).

* OT Ryan Diem (back).

* WR Roy Hall.

* RB Mike Hart (ankle).

* CB Kelvin Hayden (hamstring).

* DE Curtis Johnson.

* TE Tom Santi.

* QB Jim Sorgi (hamstring).

* TE Jacob Tamme.

The absence of the three tight ends means first-year veteran Jamie Petrowski likely will start and/or play extensively, while the absence of Diem means  former starting LT Tony Ugoh likely will start at right tackle. CB Marlin Jackson said earlier this week he doesn’t expect to play, so with Hayden out, look for Tim Jennings and perhaps Jerraud Powers to start at corner with a lot of playing time for Dante Hughes and Michael Coe.

The above list does not include the two players still on the PUP list: S Bob Sanders and K Adam Vinatieri. With Sanders and Bethea both out, look for Melvin Bullitt and Matt Giordano to start and play extensively at safety.

The absence onzalez means either second-year WR Pierre Garcon or WR Austin Collie likely will start opposite Reggie Wayne. The guess is that Garcon will start with both players playing extensively early. The absence of Hall will mean more time for younger players such as Brett McDermott and John Matthews.